A spectacular collapse on day four characterised the West Indies performance against Australia as the regional side fell to a 419 run loss in Adelaide.
Chasing 459 for victory the West Indies resumed on 34 for 4.
A procession of batsmen to and from the pavilion followed as the Windies were all out for 77 runs in 40.5 overs.
Tagenerine Chanderpaul top-scored with 17 runs, Joshua Da Silva was second best with 15, Roston Chase contributed 13 and Devon Thomas 12.
Scott Boland took three for 16, Michael Neser three for 22 and Mitchell Starc three for 29 as they wrapped up the series sweep half hour before dinner.
The Aussies won the first test by 164 runs and sit atop the nine team ICC World Test Championship with 108 points from 12 matches.
The Windies are seventh with 54 from 11.